Females are significantly smaller than males

The harsh conditions for which Malamutes were bred rewarded a strong prey drive, as food was occasionally scarce. Consequently, Malamutes may instinctively attack animals such as house cats, squirrels, rabbits, chickens, quail, and even deer (however, many households enjoy harmonious, mixed \"packs\" of cats and Malamutes). Historic competition for food is also a reason why Malamutes may regard dogs outside their own pack or team with disdain or hostility.

Malamutes dug for food when required, and digging is now a common way in which Malamutes deal with boredom. It is not uncommon to see a Malamute digging madly in pursuit of a mouse, mole, or gopher. Malamutes may also dig to escape a fenced yard, and have been known to dig escape tunnels underneath houses. This tendency to dig can be particularly frustrating to owners who maintain yards or gardens.

Malamutes were originally bred to think and act independently for the sake of protecting the sled team. Hazardous and unpredictable Arctic trail conditions rewarded the ability of a Malamute to rely on its own senses and, when necessary, override the sled driver's judgment and commands. As such, the breed is notorious for displaying a highly independent streak that manifests itself as stubbornness. Malamutes are sometimes downright insubordinate toward their human handlers and may ignore commands, particularly when young.